Sildenafil 60mg and Cardiovascular Health Considerations
It can cause problems if you normally have low blood pressure. Viagra treats erectile dysfunction (ED) in adults.
Overdose Information for Revatio
Sildenafil is rapidly absorbed following oral administration; the mean absolute bioavailability is 41% (range, 25-63%). [1][4][56][67][91][116][249] Although studies indicate that more than 90% of an oral sildenafil dose is absorbed from the GI tract, the drug undergoes extensive metabolism in the GI mucosa during absorption and on first pass through the liver, with only about 40% of a dose reaching systemic circulation unchanged. [1][4][56][67][91][116][131][249] Pharmacokinetics of the drug (as determined by peak plasma concentrations or AUC) are dose proportional over the single-dose range of 1.25-200 mg.[1][4][56][91][116][131] Peak plasma concentrations of sildenafil and its active N-desmethyl metabolite are achieved within 30-120 (median: 60) minutes following oral administration in fasting adults. [1][4][91][127][130][249] Administration with a high-fat meal delays GI absorption, with a reduction in peak plasma concentrations of about 29% and a delay in time to peak plasma concentrations of about 60 minutes; the extent of absorption is not affected. Sildenafil appears to be widely distributed in the body.
Incidence not known
[1][4][67][116][131] Sildenafil and its major circulating N-desmethyl metabolite are each approximately 96% bound to plasma proteins; protein binding reportedly is independent of plasma concentration. [1][67][91][116][131] Sildenafil is distributed to a limited extent in semen following oral administration, with less than 0.001% of a single dose appearing in semen 90 minutes after dosing in healthy individuals. [1][67] Such concentrations are unlikely to cause any effects in sexual partners exposed to the semen. [67] Plasma sildenafil concentrations appear to decline in a biphasic manner following oral administration, with a terminal elimination half-life of about 4 hours (range: 3-5 hours). [1][4][67][91][116][127][130][131] Sildenafil is metabolized principally via hepatic cytochrome P-450 (CYP) microsomal isoenzymes 3A4 (major route) and 2C9 (minor route). It’s usually taken about 1 hour before sexual activity.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 50mg | 120 + 6 Pills | 129.64€ 123.47€ | |
| Kamagra | 100mg | 32 Pills | 121.24€ 115.47€ | |
| Kamagra Oral Jelly | 100mg | 30 + 5 Sachets | 136.20€ 129.71€ | |
| Viagra Generic | 200mg | 60 + 4 Pills | 125.19€ 119.23€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ | |
| Viagra Generic | 150mg | 20 Pills | 55.02€ 52.40€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Viagra Generic | 50mg | 180 + 8 Pills | 158.82€ 151.26€ | |
| Kamagra | 100mg | 84 + 6 Pills | 264.44€ 251.85€ | |
| Viagra Generic | 150mg | 10 Pills | 36.73€ 34.98€ | |
| Kamagra Polo | 100mg | 20 Pills | 83.56€ 79.58€ | |
| Kamagra Polo | 100mg | 60 + 4 Pills | 189.39€ 180.37€ | |
| Viagra Generic | 100mg | 180 + 8 Pills | 199.37€ 189.88€ | |
| Viagra Generic | 50mg | 10 Pills | 26.87€ 25.59€ | |
| Kamagra Polo | 100mg | 120 + 6 Pills | 327.15€ 311.57€ | |
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Viagra Generic | 200mg | 270 + 10 Pills | 379.76€ 361.68€ |
Viagra dosage is not based on weight, but your age can affect your dosage.
Can I get sildenafil online?
It seems to be common to do this to try and resolve ED issues. I'm not a medical professional, but here's a document on UCSF that someone on this blog mentioned in another thread. It has a section on Penile Rehabilitation that includes some information related to your question: Best wishes. I would think your doctor would’ve checked up before prescribing it for you though, but you never know. You should at least mention to your doctor, the side effects you have felt from taking the drug.
Special Populations
See what he has to say about it. Yes, and I have spoken to her. The sildenafil is for "lung blood pressure", whatever that means. It has not impacted my pulse rate or my BP. I think I'm just sensitive to it. Viagra comes as an oral tablet that contains the active drug sildenafil.
- Sildenafil 60mg is available by prescription only.
- Store in a cool, dry place away from children.
- Do not share your medication with others.
- Inform your doctor of any allergies or medications.
Sildenafil is also available in generic form. For information on the dosage of Viagra, including 20mg sildenafil its pill form, strengths, and how to take the drug, keep reading.
| Medication | Mechanism | Common Uses | Notes |
|---|---|---|---|
| Tadalafil | PDE5 inhibitor | Erectile dysfunction, BPH | Longer duration, up to 36 hours |
| Vardenafil | PDE5 inhibitor | Erectile dysfunction | Similar to sildenafil |
| Avanafil | PDE5 inhibitor | Erectile dysfunction | Faster onset |
For a comprehensive look at Viagra, see this article.
Dosage And Administration
[1]Advise patients to take sildenafil with or without food 1 hour or, if needed, 30 minutes to 4 hours before sexual activity. [1] Inform patients that taking sildenafil with a high-fat meal may cause delayed onset. [1]Advise patient to inform their clinician of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as any concomitant illnesses. [1]Inform patients of other important precautionary information. Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.
Long-term use
Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations. \* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name © Copyright, 1959-2026, Selected Revisions April 10, 2024. American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814. The American Society of Health-System Pharmacists, Inc. represents that the database provided hereunder as formulated with a reasonable standard of care, and in conformity with professional standards in the field. This article describes typical dosages for Viagra provided by the drug’s manufacturer. When taking Viagra, always follow the dosage prescribed by your doctor. Here are details about Viagra dosages commonly used to treat erectile dysfunction (ED).
- Consult your healthcare provider before starting sildenafil.
- Monitor blood pressure regularly if prescribed anticoagulants.
- Be cautious with activities requiring alertness post-dose.
- Treatment should be part of a broader health plan.
Viagra comes as tablets that you swallow.
Are There Side Effects To Taking Sildenafil?
[1][26][67][91][131] Plasma concentrations of the active N-desmethyl metabolite are approximately 40% of those observed with sildenafil, and the metabolite reportedly accounts for about 20% of sildenafil's pharmacologic activity. [1][67][131] The N-demethylated metabolite, the major circulating metabolite, has a phosphodiesterase selectivity profile similar to that of sildenafil and an in vitro potency for PDE type 5 of approximately 50% of the parent drug. [1][116][131] Sildenafil is eliminated mainly in the feces as metabolites following oral administration. [1][67][91][116][131] In healthy adults and those with ED, approximately 80% of an oral dose is excreted as metabolites in feces and 13% is excreted in urine. Importance of instructing patients to read the manufacturer's patient information before starting sildenafil therapy and each time their prescription is refilled.
If you take more than the recommended amount of Viagra
[1]Instruct patients to avoid contraindicated medications such as regular and/or intermittent use of organic nitrates, organic nitrites (e.g., ''poppers''), and riociguat. [1]Inform patients that sildenafil is marketed for erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio®). [1] Advise patients taking Viagra® not to take Revatio® or other PDE type 5 inhibitors. [1]Advise patients of the potential for sildenafil to augment the blood pressure lowering effect of α-adrenergic blocking agents (e.g., doxazosin) and anti-hypertensive medications (e.g., amlodipine) and concomitant administration may lead to symptomatic hypotension in some patients. [1]Inform patients taking sildenafil for erectile dysfunction and with potential for cardiac risk of sexual activity (e.g., patients with preexisting cardiovascular risk factors) to refrain from further activity and seek medical attention immediately if they experience symptoms (e.g., chest pain, dizziness, nausea) upon initiation of sexual activity. Viagra tablets are available in three strengths: The following information describes commonly recommended dosages for ED.
| Key Point | Explanation | Advice |
|---|---|---|
| Take on an empty stomach or after light meal | Food may delay absorption | Wait at least 1 hour after eating |
| Do not combine with nitrates | Severe hypotension risk | Consult doctor before combining |
| Alcohol consumption | May decrease effectiveness or cause side effects | Limit or avoid alcohol during use |
| Seek medical advice for persistent side effects | To ensure safe use and address concerns | Contact healthcare provider if needed |
However, be sure to take the dosage your doctor prescribes for you.
| Condition | Recommendation | Rationale |
|---|---|---|
| Temperature | Store at room temperature (20-25°C) | Prevents degradation |
| Light exposure | Keep in original container, away from light | Maintains drug stability |
| Humidity | Keep dry, avoid bathroom storage | Prevents moisture damage |
Your doctor will determine the best dosage to fit your needs. You’ll likely start with a Viagra dose of 50 mg. You’ll typically take Viagra about 1 hour before sex. You can take the drug 30 minutes to 4 hours before you anticipate sexual activity. Based on how well you respond to this dosage and any side effects you have, your doctor may either increase your dose up to the maximum of 100 mg or decrease your dose to 25 mg.
Does Either Medication Reverse ED?
[1]Advise patients to seek immediate medical attention for a sudden loss of vision in one or both eyes while sildenafil citrate 120 mg taking sildenafil. [1] Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including possible permanent loss of vision. [1]Advise patients to seek prompt medical attention in the event of sudden decrease or loss of hearing while taking sildenafil. [1] These events may be accompanied by tinnitus and dizziness. [1]Advise patients to seek prompt medical attention for an erection that lasts more than 4 hours.
Other Medical Problems
[1] If it is not treated right away, priapism can permanently damage the penis. [1]Inform patients taking sildenafil for erectile dysfunction that the drug offers no protection against sexually transmitted diseases and patients should use necessary protective measures to guard against such diseases, including the human immunodeficiency virus (HIV). [1]Instruct the patient to seek medical attention immediately if they take too much sildenafil. [1]Inform patients of the risk of symptomatic low blood pressure (e.g., dizziness, lightheadedness, fainting). [1] Monitor blood pressure when administering sildenafil in combination with blood pressure lowering drugs (e.g., α-adrenergic blocking agents). You should not take Viagra more than once per day.
Patient Information for Revatio
The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty or merchantability and/or fitness for a particular purpose, with respect to such database and specifically disclaims all such warranties and representations. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the database if provided for informational purposes only. The entire monograph for a drug should be reviewed for a throrough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc.
Viagra form
does not endorse or recommend the use of any drug in the database. The information contained in the database is not a substitute for medical care or treatment by a licensed health care provider. For those of you taking Sildenafil (Viagra) to help with ED, sildenafil oral jelly 100mg lovegra I am asking this dosing question. I just got my first script from the online pharmacy my doctor sent it to, and the bottle says "Take two pills daily and 3 more 1 hour before sexual activity." And then on the "appointed day" take 5? Go to the Prostate Cancer Support Group. And you should only take it as needed. Viagra is meant to be used as a long-term treatment.
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